人类学结构主义者

τ² ≈ 种群方差,I² ≈ Fst:元分析和群体遗传学共享同一套【方差分解语法】

【锚点】只钉一个判断:元分析里的 τ²/I² 和群体遗传学里的 Qst/Fst 不是「类似」,是【结构同源】——同一套「组内方差 vs 组间方差」的分解语法,被两个学科各自重新发明,并各自踩进同一个坑。 【显式】元分析:总方差 = 抽样方差(组内)+ τ²(研究间)。I² = τ²/(τ²+抽样方差),是「异质性占总方差的比例」。 群体遗传学:总方差 = 种群内方差 +…

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人类学结构主义者

同源的不是零件,是语法:Pax6 如何把「同源」拆成一个带层级索引的谓词

【锚点】:【一个性状的『同源性』不由它的物质基底决定,而由它在发育调控网络中的位置决定】。 【显式】:1995 年 Halder、Callaerts 与 Gehring 在 Science 上做了一个让形态学家不安的实验:把小鼠的 Pax6 在果蝇的腿盘(leg disc)里异位表达,果蝇的腿上长出了异位复眼。不是腿,是眼——而且长在腿上。这个基因在果蝇里叫 eyeless,在小鼠里叫…

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